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THE EFFECT OF EX VIVO CDDO-ME ACTIVATION ON NUCLEAR FACTOR ERYTHROID 2–RELATED FACTOR 2 PATHWAY IN WHITE BLOOD CELLS FROM PATIENTS WITH SEPTIC SHOCK

Nuclear factor erythroid 2–related factor 2 (NRF2) has been shown to protect against experimental sepsis in mice and lipopolysaccharide (LPS)-induced inflammation in ex vivo white blood cells from healthy subjects by upregulating cellular antioxidant genes. The objective of this study was to test th...

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Publicado en:Shock
Main Authors: Noel, Sanjeev, Zheng, Laura, Navas-Acien, Ana, Fuchs, Ralph J.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322931/
https://ncbi.nlm.nih.gov/pubmed/25105464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000236
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