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Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions.

Rat liver membrane adenylate cyclase (EC 4.6.1.1) that has been stimulated more than 10-fold by cholera toxin (choleragen) has a 3-fold greater sensitivity to stimulation by glucagon. Choleragen similarly increases the sensitivity of cyclase to other peptide (ACTH, vasoactive intestinal polypeptide)...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Bennett, V, O'Keefe, E, Cuatrecasaş, P
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1975
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432234/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/164020/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.1.33
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