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Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions.

Rat liver membrane adenylate cyclase (EC 4.6.1.1) that has been stimulated more than 10-fold by cholera toxin (choleragen) has a 3-fold greater sensitivity to stimulation by glucagon. Choleragen similarly increases the sensitivity of cyclase to other peptide (ACTH, vasoactive intestinal polypeptide)...

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Detalles Bibliográficos
Main Authors: Bennett, V, O'Keefe, E, Cuatrecasaş, P
Formato: Artigo
Idioma:Inglês
Publicado: 1975
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC432234/
https://ncbi.nlm.nih.gov/pubmed/164020
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