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Targeting the Prodromal Stage of Alzheimer’s Disease: Bioenergetic and Mitochondrial Opportunities

Alzheimer’s disease (AD) has a complex and progressive neurodegenerative phenotype, with hypometabolism and impaired mitochondrial bioenergetics among the earliest pathogenic events. Bioenergetic deficits are well documented in preclinical models of mammalian aging and AD, emerge early in the prodro...

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Bibliografiska uppgifter
I publikationen:Neurotherapeutics
Huvudupphovsmän: Caldwell, Charles C., Yao, Jia, Brinton, Roberta Diaz
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322082/
https://ncbi.nlm.nih.gov/pubmed/25534394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-014-0324-8
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