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Targeting the Prodromal Stage of Alzheimer’s Disease: Bioenergetic and Mitochondrial Opportunities

Alzheimer’s disease (AD) has a complex and progressive neurodegenerative phenotype, with hypometabolism and impaired mitochondrial bioenergetics among the earliest pathogenic events. Bioenergetic deficits are well documented in preclinical models of mammalian aging and AD, emerge early in the prodro...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Neurotherapeutics
Päätekijät: Caldwell, Charles C., Yao, Jia, Brinton, Roberta Diaz
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322082/
https://ncbi.nlm.nih.gov/pubmed/25534394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-014-0324-8
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