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Decline in Mitochondrial Bioenergetics and Shift to Ketogenic Profile in Brain During Reproductive Senescence
BACKGROUND: We have previously demonstrated that mitochondrial bioenergetic deficits precede Alzheimer’s pathology in the female triple transgenic Alzheimer’s (3xTgAD) mouse model. Herein, we sought to determine the impact of reproductive senescence on mitochondrial function in the normal non-transg...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3200365/ https://ncbi.nlm.nih.gov/pubmed/20538040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2010.06.002 |
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