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Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

Mitochondrial dysfunction has been proposed to play a pivotal role in neurodegenerative diseases, including Alzheimer's disease (AD). To address whether mitochondrial dysfunction precedes the development of AD pathology, we conducted mitochondrial functional analyses in female triple transgenic...

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Detalhes bibliográficos
Main Authors: Yao, Jia, Irwin, Ronald W., Zhao, Liqin, Nilsen, Jon, Hamilton, Ryan T., Brinton, Roberta Diaz
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732886/
https://ncbi.nlm.nih.gov/pubmed/19667196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903563106
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