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Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid

Previously, we demonstrated that reproductive senescence was associated with mitochondrial deficits comparable to those of female triple-transgenic Alzheimer’s mice (3xTgAD). Herein, we investigated the impact of chronic ovarian hormone deprivation and 17β-estradiol (E2) replacement on mitochondrial...

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Detalhes bibliográficos
Main Authors: Yao, Jia, Irwin, Ronald, Chen, Shuhua, Hamilton, Ryan, Cadenas, Enrique, Brinton, Roberta Diaz
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181273/
https://ncbi.nlm.nih.gov/pubmed/21514693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.03.001
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