Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer

JAK/STAT3 is one of the major signaling pathways that is aberrantly activated in ovarian cancer and associated with tumor progression and poor prognosis in ovarian cancer patients. In this study, we evaluated the therapeutic potential of targeting JAK/STAT3 signaling in ovarian cancer using a perito...

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I publikationen:Mol Cancer Ther
Huvudupphovsmän: Wen, Wei, Liang, Wei, Wu, Jun, Kowolik, Claudia M., Buettner, Ralf, Scuto, Anna, Hsieh, Meng-Yin, Hong, Hao, Brown, Christine E., Forman, Stephen J., Horne, David, Morgan, Robert, Wakabayashi, Mark, Dellinger, Thanh H., Han, Ernest S., Yim, John H., Jove, Richard
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321961/
https://ncbi.nlm.nih.gov/pubmed/25319391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0077
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