Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer

JAK/STAT3 is one of the major signaling pathways that is aberrantly activated in ovarian cancer and associated with tumor progression and poor prognosis in ovarian cancer patients. In this study, we evaluated the therapeutic potential of targeting JAK/STAT3 signaling in ovarian cancer using a perito...

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Bibliografske podrobnosti
izdano v:Mol Cancer Ther
Main Authors: Wen, Wei, Liang, Wei, Wu, Jun, Kowolik, Claudia M., Buettner, Ralf, Scuto, Anna, Hsieh, Meng-Yin, Hong, Hao, Brown, Christine E., Forman, Stephen J., Horne, David, Morgan, Robert, Wakabayashi, Mark, Dellinger, Thanh H., Han, Ernest S., Yim, John H., Jove, Richard
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321961/
https://ncbi.nlm.nih.gov/pubmed/25319391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0077
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