Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer

JAK/STAT3 is one of the major signaling pathways that is aberrantly activated in ovarian cancer and associated with tumor progression and poor prognosis in ovarian cancer patients. In this study, we evaluated the therapeutic potential of targeting JAK/STAT3 signaling in ovarian cancer using a perito...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer Ther
Prif Awduron: Wen, Wei, Liang, Wei, Wu, Jun, Kowolik, Claudia M., Buettner, Ralf, Scuto, Anna, Hsieh, Meng-Yin, Hong, Hao, Brown, Christine E., Forman, Stephen J., Horne, David, Morgan, Robert, Wakabayashi, Mark, Dellinger, Thanh H., Han, Ernest S., Yim, John H., Jove, Richard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321961/
https://ncbi.nlm.nih.gov/pubmed/25319391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0077
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