Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway

BACKGROUND: Histone acetyltransferase (HAT) inhibitors can inhibit proliferation and induce apoptosis in cancer cell lines. The novel cell-permeable p300/CREB-binding protein (CBP)-selective HAT inhibitor HATi II can reduce histone H3 acetylation and induce chromatin condensation in HeLa cells. Here...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Xu, Li-Xiao, Li, Zhi-Heng, Tao, Yan-Fang, Li, Rong-Hu, Fang, Fang, Zhao, He, Li, Gang, Li, Yan-Hong, Wang, Jian, Feng, Xing, Pan, Jian
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321714/
https://ncbi.nlm.nih.gov/pubmed/25523932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0108-3
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