IRF5 is elevated in childhood-onset SLE and regulated by histone acetyltransferase and histone deacetylase inhibitors

Interferon regulatory factor 5 (IRF5) plays a critical role in the induction of type I interferon, proinflammatory cytokines and chemokines, and participates in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus (SLE). However, the relationship between IRF5 and childhood-on...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Shu, Jin, Li, Ling, Zhou, Lan-Bo, Qian, Jun, Fan, Zhi-Dan, Zhuang, Li-Li, Wang, Lu-Lu, Jin, Rui, Yu, Hai-Guo, Zhou, Guo-Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564555/
https://ncbi.nlm.nih.gov/pubmed/28525378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17586
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