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Up-regulation of IRF-3 expression through GATA-1 acetylation by histone deacetylase inhibitor in lung adenocarcinoma A549 cells

Interferon regulatory factor 3 (IRF-3) is an important transcription factor for interferon genes. Although its functional activation by viral infection has been widely explicated, the regulatory mechanism of IRF-3 gene expression in cancer cells is poorly understood. In this study, we demonstrated t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Lu-Lu, Zhou, Lan-Bo, Shu, Jin, Li, Nan-Nan, Zhang, Hui-Wen, Jin, Rui, Zhuang, Li-Li, Zhou, Guo-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652676/
https://ncbi.nlm.nih.gov/pubmed/29100282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18371
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