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Kinetics of sickle cell biorheology and implications for painful vasoocclusive crisis

We developed a microfluidics-based model to quantify cell-level processes modulating the pathophysiology of sickle cell disease (SCD). This in vitro model enabled quantitative investigations of the kinetics of cell sickling, unsickling, and cell rheology. We created short-term and long-term hypoxic...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Du, E, Diez-Silva, Monica, Kato, Gregory J., Dao, Ming, Suresh, Subra
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321273/
https://ncbi.nlm.nih.gov/pubmed/25605910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424111112
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