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Kinetics of sickle cell biorheology and implications for painful vasoocclusive crisis

We developed a microfluidics-based model to quantify cell-level processes modulating the pathophysiology of sickle cell disease (SCD). This in vitro model enabled quantitative investigations of the kinetics of cell sickling, unsickling, and cell rheology. We created short-term and long-term hypoxic...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Du, E, Diez-Silva, Monica, Kato, Gregory J., Dao, Ming, Suresh, Subra
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321273/
https://ncbi.nlm.nih.gov/pubmed/25605910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424111112
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