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Proposal for the biologically active conformation of opiates and enkephalin.

A model for the opiate receptor has been defined by using a computer-based molecular display and x-ray crystallographic input data. The model can explain the stereochemical fashion in which the morphine, morphinan, and oripavine classes of compounds interact with the receptor. The minimal structural...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Gorin, F A, Marshall, G R
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1977
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432125/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/270758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.11.5179
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