Proposal for the biologically active conformation of opiates and enkephalin.
A model for the opiate receptor has been defined by using a computer-based molecular display and x-ray crystallographic input data. The model can explain the stereochemical fashion in which the morphine, morphinan, and oripavine classes of compounds interact with the receptor. The minimal structural...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1977
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432125/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/270758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.11.5179 |
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