β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma

BACKGROUND: The Wnt/beta-catenin and the Hedgehog (Hh) pathway interact in various cell types while eliciting opposing or synergistic cellular effects. Both pathways are known as exclusive drivers of two distinct molecular subtypes of medulloblastoma (MB). In sonic hedgehog (Shh)-driven MB, activati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer
Prif Awduron: Zinke, Jenny, Schneider, Fabian T, Harter, Patrick N, Thom, Sonja, Ziegler, Nicole, Toftgård, Rune, Plate, Karl H, Liebner, Stefan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Short Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320815/
https://ncbi.nlm.nih.gov/pubmed/25645196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0294-4
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