Sonic Hedgehog Acts as a Negative Regulator of β-Catenin Signaling in the Adult Tongue Epithelium

Wnt/β-catenin signaling has been implicated in taste papilla development; however, its role in epithelial maintenance and tumor progression in the adult tongue remains elusive. We show Wnt/β-catenin pathway activation in reporter mice and by nuclear β-catenin staining in the epithelium and taste pap...

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Bibliografiske detaljer
Main Authors: Schneider, Fabian T., Schänzer, Anne, Czupalla, Cathrin J., Thom, Sonja, Engels, Knut, Schmidt, Mirko H.H., Plate, Karl H., Liebner, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2010
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893682/
https://ncbi.nlm.nih.gov/pubmed/20508033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091079
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