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Molecular characterization of Wnt pathway and function of β-catenin overexpression in medulloblastoma cell lines

Medulloblastoma (MB) is the most common malignant childhood brain tumor. MB is currently classified into four molecular subgroups (Wnt, Shh, Group 3, and Group 4). The wingless (Wnt) pathway is responsible for embryonic development and is deregulated in MB. We analyzed the activation of the Wnt path...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: Geron, Lenisa, Salomão, Karina Bezerra, Borges, Kleiton Silva, Andrade, Augusto Faria, Corrêa, Carolina Alves Pereira, Scrideli, Carlos Alberto, Tone, Luiz Gonzaga
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269366/
https://ncbi.nlm.nih.gov/pubmed/30374857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-018-0260-2
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