Chromosomal heterogeneity and instability characterize pediatric medulloblastoma cell lines and affect neoplastic phenotype

Chromosomal heterogeneity is a hallmark of most tumors and it can drive critical events as growth advantages, survival advantages, progression and karyotypic evolution. Medulloblastoma (MB) is the most common malignant central nervous system tumor in children. This work attempted to investigate chro...

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Hauptverfasser: Castro-Gamero, Angel Mauricio, Borges, Kleiton Silva, Lira, Regia Caroline, Andrade, Augusto Faria, Fedatto, Paola Fernanda, Cruzeiro, Gustavo Alencastro Veiga, Silva, Ricardo Bonfim, Fontes, Aparecida Maria, Valera, Elvis Terci, Bobola, Michael, Scrideli, Carlos Alberto, Tone, Luiz Gonzaga
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2013
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967617/
https://ncbi.nlm.nih.gov/pubmed/23325114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-012-9529-z
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