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Prostaglandin regulation of macrophage collagenase production.

The production of collagenase (EC 3.4.24.3) by endotoxin-stimulated macrophages was significantly inhibited by indomethacin, indicating that prostaglandins (PGs) mediate this effect. Inhibitions of collagenase production by indomethacin was overcome by addition of exogenous PGE2 at 10 nM whereas the...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wahl, L M, Olsen, C E, Sandberg, A L, Mergenhagen, S E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1977
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/200941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.11.4955
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