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Prostaglandin regulation of macrophage collagenase production.

The production of collagenase (EC 3.4.24.3) by endotoxin-stimulated macrophages was significantly inhibited by indomethacin, indicating that prostaglandins (PGs) mediate this effect. Inhibitions of collagenase production by indomethacin was overcome by addition of exogenous PGE2 at 10 nM whereas the...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Wahl, L M, Olsen, C E, Sandberg, A L, Mergenhagen, S E
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1977
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/200941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.11.4955
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