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Prostaglandin regulation of macrophage collagenase production.

The production of collagenase (EC 3.4.24.3) by endotoxin-stimulated macrophages was significantly inhibited by indomethacin, indicating that prostaglandins (PGs) mediate this effect. Inhibitions of collagenase production by indomethacin was overcome by addition of exogenous PGE2 at 10 nM whereas the...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Wahl, L M, Olsen, C E, Sandberg, A L, Mergenhagen, S E
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1977
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/200941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.11.4955
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