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Liraglutide, leptin, and their combined effects on feeding: additive intake reduction through common intracellular signaling mechanisms

AIMS: Glucagon like peptide-1 receptor (GLP-1R) agonists and leptin each exert anorexigenic effects. In combination, the intake inhibitory and weight loss effects are greater than either treatment alone, however the mechanisms unclear. MATERIALS AND METHODS: Effects of liraglutide (a long-acting GLP...

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Detalhes bibliográficos
Publicado no:Diabetes Obes Metab
Main Authors: Kanoski, Scott E., Ong, Zhi Yi, Fortin, Samantha M., Schlessinger, Elizabeth S., Grill, Harvey J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320650/
https://ncbi.nlm.nih.gov/pubmed/25475828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12423
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