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Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive fashion

BACKGROUND: The physiological control of feeding behavior involves modulation of the intake inhibitory effects of gastrointestinal satiation signaling via endogenous hindbrain leptin receptor (LepR) and glucagon-like-peptide-1 receptor (GLP-1R) activation. DESIGN AND RESULTS: Using a variety of dose...

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Detalhes bibliográficos
Main Authors: Zhao, Shiru, Kanoski, Scott E., Yan, Jianqun, Grill, Harvey J., Hayes, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335926/
https://ncbi.nlm.nih.gov/pubmed/22249232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2011.265
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