Intracellular signals mediating the food intake suppressive effects of hindbrain glucagon-like-peptide-1 receptor activation

Glucagon-like-peptide-1 receptor (GLP-1R) activation within the nucleus tractus solitarius (NTS) suppresses food intake and body weight (BW), but the intracellular signals mediating these effects are unknown. Here, hindbrain (4(th) icv) GLP-1R activation by Exendin-4 increased PKA and MAPK activity...

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Huvudupphovsmän: Hayes, Matthew R., Leichner, Theresa M., Zhao, Shiru, Lee, Grace S., Chowansky, Amy, Zimmer, Derek, De Jonghe, Bart C., Kanoski, Scott E., Grill, Harvey J., Bence, Kendra K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108145/
https://ncbi.nlm.nih.gov/pubmed/21356521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.02.001
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