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2-Aminopurine-induced mutagenesis in T4 bacteriophage: a model relating mutation frequency to 2-aminopurine incorporation in DNA.

We measured the in vivo incorporation of 2-aminopurine into DNA of T4 bacteriophage allelic for gene 43 (DNA polymerase), mutator (L56), 43+, and antimutator (L141). The magnitude of incorporation (mol/mol of Thy) was 1/1500 in L56, 1/1600 in 43+, and 1/8900 in L141. The incorporation ratio L56:43+:...

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Bibliografiske detaljer
Main Authors: Goodman, M F, Hopkins, R, Gore, W C
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC432044/
https://ncbi.nlm.nih.gov/pubmed/270713
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