Mechanism of 2-aminopurine mutagenesis in mouse T-lymphosarcoma cells.
We investigated the mechanism of action of 2-aminopurine (Apur) in eucaryotic cells. By analogy with studies in procaryotic systems, the base analog is presumed to incorporate into DNA predominantly opposite T where, upon subsequent DNA replication, it can mispair with C, inducing an A:T leads to G:...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369902/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6983647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.9.1096-1103.1982 |
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