Mechanism of 2-aminopurine mutagenesis in mouse T-lymphosarcoma cells.

We investigated the mechanism of action of 2-aminopurine (Apur) in eucaryotic cells. By analogy with studies in procaryotic systems, the base analog is presumed to incorporate into DNA predominantly opposite T where, upon subsequent DNA replication, it can mispair with C, inducing an A:T leads to G:...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Caras, I W, MacInnes, M A, Persing, D H, Coffino, P, Martin, D W
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1982
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369902/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6983647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.9.1096-1103.1982
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