Mechanism of 2-aminopurine mutagenesis in mouse T-lymphosarcoma cells.

We investigated the mechanism of action of 2-aminopurine (Apur) in eucaryotic cells. By analogy with studies in procaryotic systems, the base analog is presumed to incorporate into DNA predominantly opposite T where, upon subsequent DNA replication, it can mispair with C, inducing an A:T leads to G:...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Caras, I W, MacInnes, M A, Persing, D H, Coffino, P, Martin, D W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1982
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC369902/
https://ncbi.nlm.nih.gov/pubmed/6983647
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