Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1

Malignant glioma belong to the most aggressive neoplasms in humans with no successful treatment available. Patients suffering from glioblastoma multiforme (GBM), the highest-grade glioma, have an average survival time of only around one year after diagnosis. Both microglia and peripheral macrophages...

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Vydáno v:PLoS One
Hlavní autoři: Szulzewsky, Frank, Pelz, Andreas, Feng, Xi, Synowitz, Michael, Markovic, Darko, Langmann, Thomas, Holtman, Inge R., Wang, Xi, Eggen, Bart J. L., Boddeke, Hendrikus W. G. M., Hambardzumyan, Dolores, Wolf, Susanne A., Kettenmann, Helmut
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320099/
https://ncbi.nlm.nih.gov/pubmed/25658639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116644
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