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Association of Mitochondrial DNA levels with Frailty and All-Cause Mortality
Mitochondrial function is altered with age, and variants in mitochondrial DNA (mtDNA) modulate risk for several age-related disease states. However, the association of mtDNA copy number, a readily available marker which reflects mitochondrial depletion, energy reserves and oxidative stress, on aging...
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Publié dans: | J Mol Med (Berl) |
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Auteurs principaux: | , , , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319988/ https://ncbi.nlm.nih.gov/pubmed/25471480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1233-3 |
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