Polymorphisms in the Mitochondrial DNA Control Region and Frailty in Older Adults

BACKGROUND: Mitochondria contribute to the dynamics of cellular metabolism, the production of reactive oxygen species, and apoptotic pathways. Consequently, mitochondrial function has been hypothesized to influence functional decline and vulnerability to disease in later life. Mitochondrial genetic...

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Main Authors: Moore, Ann Z., Biggs, Mary L., Matteini, Amy, O'Connor, Ashley, McGuire, Sarah, Beamer, Brock A., Fallin, M. Danielle, Fried, Linda P., Walston, Jeremy, Chakravarti, Aravinda, Arking, Dan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883558/
https://ncbi.nlm.nih.gov/pubmed/20548781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011069
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