Herpes Simplex Virus 2 (HSV-2) Infected Cell Proteins Are among the Most Dominant Antigens of a Live-Attenuated HSV-2 Vaccine

Virion glycoproteins such as glycoprotein D (gD) are believed to be the dominant antigens of herpes simplex virus 2 (HSV-2). We have observed that mice immunized with a live HSV-2 ICP0 (-) mutant virus, HSV-2 0ΔNLS, are 10 to 100 times better protected against genital herpes than mice immunized with...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Geltz, Joshua J., Gershburg, Edward, Halford, William P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319894/
https://ncbi.nlm.nih.gov/pubmed/25658852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116091
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