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Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2
Herpes simplex virus 2 (HSV-2) 0ΔNLS is a live HSV-2 ICP0 (-) mutant vaccine strain that is profoundly attenuated in vivo due to its interferon-hypersensitivity. Recipients of the HSV-2 0ΔNLS vaccine are resistant to high-dose HSV-2 challenge as evidenced by profound reductions in challenge virus sp...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682860/ https://ncbi.nlm.nih.gov/pubmed/26670699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145228 |
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