Retinal Cone Photoreceptors Require Phosducin-Like Protein 1 for G Protein Complex Assembly and Signaling

G protein β subunits (Gβ) play essential roles in phototransduction as part of G protein βγ (Gβγ) and regulator of G protein signaling 9 (RGS9)-Gβ(5) heterodimers. Both are obligate dimers that rely on the cytosolic chaperone CCT and its co-chaperone PhLP1 to form complexes from their nascent polype...

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Veröffentlicht in:PLoS One
Hauptverfasser: Tracy, Christopher M., Kolesnikov, Alexander V., Blake, Devon R., Chen, Ching-Kang, Baehr, Wolfgang, Kefalov, Vladimir J., Willardson, Barry M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319785/
https://ncbi.nlm.nih.gov/pubmed/25659125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117129
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