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Phosphorylation at Serine 21 in G protein-coupled receptor kinase 1 (GRK1) is required for normal kinetics of dark adaption in rod but not cone photoreceptors

Timely recovery of the light response in photoreceptors requires efficient inactivation of photoactivated rhodopsin. This process is initiated by phosphorylation of its carboxyl terminus by G protein-coupled receptor kinase 1 (GRK1). Previously, we showed that GRK1 is phosphorylated in the dark at S...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Kolesnikov, Alexander V., Chrispell, Jared D., Osawa, Shoji, Kefalov, Vladimir J., Weiss, Ellen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043924/
https://ncbi.nlm.nih.gov/pubmed/31908030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902535R
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