Phosphorylation of G Protein-coupled Receptor Kinase 1 (GRK1) Is Regulated by Light but Independent of Phototransduction in Rod Photoreceptors

Phosphorylation of rhodopsin by G protein-coupled receptor kinase 1 (GRK1, or rhodopsin kinase) is critical for the deactivation of the phototransduction cascade in vertebrate photoreceptors. Based on our previous studies in vitro, we predicted that Ser(21) in GRK1 would be phosphorylated by cAMP-de...

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Detalhes bibliográficos
Main Authors: Osawa, Shoji, Jo, Rebecca, Xiong, Yubin, Reidel, Boris, Tserentsoodol, Nomingerel, Arshavsky, Vadim Y., Iuvone, P. Michael, Weiss, Ellen R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121460/
https://ncbi.nlm.nih.gov/pubmed/21504899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230904
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