Phosphorylation of G Protein-coupled Receptor Kinase 1 (GRK1) Is Regulated by Light but Independent of Phototransduction in Rod Photoreceptors

Phosphorylation of rhodopsin by G protein-coupled receptor kinase 1 (GRK1, or rhodopsin kinase) is critical for the deactivation of the phototransduction cascade in vertebrate photoreceptors. Based on our previous studies in vitro, we predicted that Ser(21) in GRK1 would be phosphorylated by cAMP-de...

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Autori principali: Osawa, Shoji, Jo, Rebecca, Xiong, Yubin, Reidel, Boris, Tserentsoodol, Nomingerel, Arshavsky, Vadim Y., Iuvone, P. Michael, Weiss, Ellen R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121460/
https://ncbi.nlm.nih.gov/pubmed/21504899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230904
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