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Cystinotic fibroblasts accumulate cystine from intracellular protein degradation.

Fibroblasts derived from patients with cystinosis, an autosomal recessive condition, accumulate the disulfide amino acid cystine within lysosomes. The metabolic defect leading to the cystine accumulation and the source from which the cystine is derived are unknown. In this report we present data sho...

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Dettagli Bibliografici
Autori principali: Thoene, J G, Oshima, R G, Ritchie, D G, Schneider, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1977
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC431972/
https://ncbi.nlm.nih.gov/pubmed/270698
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