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Designer aminoglycosides prevent cochlear hair cell loss and hearing loss

Bacterial infections represent a rapidly growing challenge to human health. Aminoglycosides are widely used broad-spectrum antibiotics, but they inflict permanent hearing loss in up to ~50% of patients by causing selective sensory hair cell loss. Here, we hypothesized that reducing aminoglycoside en...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Huth, Markus E., Han, Kyu-Hee, Sotoudeh, Kayvon, Hsieh, Yi-Ju, Effertz, Thomas, Vu, Andrew A., Verhoeven, Sarah, Hsieh, Michael H., Greenhouse, Robert, Cheng, Alan G., Ricci, Anthony J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319422/
https://ncbi.nlm.nih.gov/pubmed/25555219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77424
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