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Functional Hair Cell Mechanotransducer Channels Are Required for Aminoglycoside Ototoxicity

Aminoglycosides (AG) are commonly prescribed antibiotics with potent bactericidal activities. One main side effect is permanent sensorineural hearing loss, induced by selective inner ear sensory hair cell death. Much work has focused on AG's initiating cell death processes, however, fewer studi...

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Hlavní autoři: Alharazneh, Abdelrahman, Luk, Lauren, Huth, Markus, Monfared, Ashkan, Steyger, Peter S., Cheng, Alan G., Ricci, Anthony J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144223/
https://ncbi.nlm.nih.gov/pubmed/21818312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022347
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