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Hsp70 inhibits aminoglycoside-induced hearing loss and cochlear hair cell death

Sensory hair cells of the inner ear are sensitive to death from aging, noise trauma, and ototoxic drugs. Ototoxic drugs include the aminoglycoside antibiotics and the antineoplastic agent cisplatin. Exposure to aminoglycosides results in hair cell death that is mediated by specific apoptotic protein...

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Detalhes bibliográficos
Main Authors: Taleb, Mona, Brandon, Carlene S., Lee, Fu-Shing, Harris, Kelly C., Dillmann, Wolfgang H., Cunningham, Lisa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728278/
https://ncbi.nlm.nih.gov/pubmed/19145477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-008-0097-2
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