HIF2α signaling inhibits adherens junctional disruption in acute lung injury

Vascular endothelial barrier dysfunction underlies diseases such as acute respiratory distress syndrome (ARDS), characterized by edema and inflammatory cell infiltration. The transcription factor HIF2α is highly expressed in vascular endothelial cells (ECs) and may regulate endothelial barrier funct...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Gong, Haixia, Rehman, Jalees, Tang, Haiyang, Wary, Kishore, Mittal, Manish, Chatturvedi, Pallavi, Zhao, Youyang, Komorova, Yulia A., Vogel, Stephen M., Malik, Asrar B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319409/
https://ncbi.nlm.nih.gov/pubmed/25574837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77701
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