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HIF2α signaling inhibits adherens junctional disruption in acute lung injury

Vascular endothelial barrier dysfunction underlies diseases such as acute respiratory distress syndrome (ARDS), characterized by edema and inflammatory cell infiltration. The transcription factor HIF2α is highly expressed in vascular endothelial cells (ECs) and may regulate endothelial barrier funct...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Gong, Haixia, Rehman, Jalees, Tang, Haiyang, Wary, Kishore, Mittal, Manish, Chatturvedi, Pallavi, Zhao, Youyang, Komorova, Yulia A., Vogel, Stephen M., Malik, Asrar B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319409/
https://ncbi.nlm.nih.gov/pubmed/25574837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77701
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