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Correlations between long inverted repeat (LIR) features, deletion size and distance from breakpoint in human gross gene deletions

Long inverted repeats (LIRs) have been shown to induce genomic deletions in yeast. In this study, LIRs were investigated within ±10 kb spanning each breakpoint from 109 human gross deletions, using Inverted Repeat Finder (IRF) software. LIR number was significantly higher at the breakpoint regions,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Glavni avtor: Aygun, Nevim
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319165/
https://ncbi.nlm.nih.gov/pubmed/25657065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08300
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