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Correlations between long inverted repeat (LIR) features, deletion size and distance from breakpoint in human gross gene deletions

Long inverted repeats (LIRs) have been shown to induce genomic deletions in yeast. In this study, LIRs were investigated within ±10 kb spanning each breakpoint from 109 human gross deletions, using Inverted Repeat Finder (IRF) software. LIR number was significantly higher at the breakpoint regions,...

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Publicado en:Sci Rep
Autor principal: Aygun, Nevim
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319165/
https://ncbi.nlm.nih.gov/pubmed/25657065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08300
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