Neurotrophin Signaling via TrkB and TrkC Receptors Promotes the Growth of Brain Tumor-initiating Cells

Neurotrophins and their receptors are frequently expressed in malignant gliomas, yet their functions are largely unknown. Previously, we have shown that p75 neurotrophin receptor is required for glioma invasion and proliferation. However, the role of Trk receptors has not been examined. In this stud...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Lawn, Samuel, Krishna, Niveditha, Pisklakova, Alexandra, Qu, Xiaotao, Fenstermacher, David A., Fournier, Michelle, Vrionis, Frank D., Tran, Nam, Chan, Jennifer A., Kenchappa, Rajappa S., Forsyth, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319045/
https://ncbi.nlm.nih.gov/pubmed/25538243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599373
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