Neurotrophin Signaling via TrkB and TrkC Receptors Promotes the Growth of Brain Tumor-initiating Cells

Neurotrophins and their receptors are frequently expressed in malignant gliomas, yet their functions are largely unknown. Previously, we have shown that p75 neurotrophin receptor is required for glioma invasion and proliferation. However, the role of Trk receptors has not been examined. In this stud...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Lawn, Samuel, Krishna, Niveditha, Pisklakova, Alexandra, Qu, Xiaotao, Fenstermacher, David A., Fournier, Michelle, Vrionis, Frank D., Tran, Nam, Chan, Jennifer A., Kenchappa, Rajappa S., Forsyth, Peter A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319045/
https://ncbi.nlm.nih.gov/pubmed/25538243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599373
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