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Human Autoantibodies Specific for Neurotrophin Receptors TrkA, TrkB, and TrkC Protect against Lethal Trypanosoma cruzi Infection in Mice

Patients with Chagas’ disease remain asymptomatic for many years, presumably by keeping the etiological agent Trypanosoma cruzi in check through protective immunity against. Recently, we found that T. cruzi uses TrkA, a receptor tyrosine kinase responsive to neurotrophin nerve growth factor in verte...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lu, Bo, Alroy, Joseph, Luquetti, Alejandro O., PereiraPerrin, Mercio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570131/
https://ncbi.nlm.nih.gov/pubmed/18832578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080514
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