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Human Autoantibodies Specific for Neurotrophin Receptors TrkA, TrkB, and TrkC Protect against Lethal Trypanosoma cruzi Infection in Mice

Patients with Chagas’ disease remain asymptomatic for many years, presumably by keeping the etiological agent Trypanosoma cruzi in check through protective immunity against. Recently, we found that T. cruzi uses TrkA, a receptor tyrosine kinase responsive to neurotrophin nerve growth factor in verte...

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Detalhes bibliográficos
Main Authors: Lu, Bo, Alroy, Joseph, Luquetti, Alejandro O., PereiraPerrin, Mercio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570131/
https://ncbi.nlm.nih.gov/pubmed/18832578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080514
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