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11β-Hydroxysteroid Dehydrogenase Activity in the Brain Does Not Contribute to Systemic Interconversion of Cortisol and Cortisone in Healthy Men

CONTEXT AND OBJECTIVE: 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) catalyses regeneration of cortisol in liver, adipose tissue, and skeletal muscle, making a substantial contribution to circulating cortisol as demonstrated in humans by combining stable isotope tracer infusion with arteriovenou...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Kilgour, Alixe H.M., Semple, Scott, Marshall, Ian, Andrews, Peter, Andrew, Ruth, Walker, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318893/
https://ncbi.nlm.nih.gov/pubmed/25393644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3277
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