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A docking interface in the cyclin Cln2 promotes multisite phosphorylation of substrates and timely cell cycle entry

BACKGROUND: Eukaryotic cell division is driven by cyclin-dependent kinases (CDKs). Distinct cyclin-CDK complexes are specialized to drive different cell cycle events, though the molecular foundations for these specializations are only partly understood. In budding yeast, the decision to begin a new...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Biol
Hauptverfasser: Bhaduri, Samyabrata, Valk, Ervin, Winters, Matthew J., Gruessner, Brian, Loog, Mart, Pryciak, Peter M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318751/
https://ncbi.nlm.nih.gov/pubmed/25619768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.11.069
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