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Regulation of cyclin-substrate docking by a G1 arrest signaling pathway and the Cdk inhibitor Far1

Eukaryotic cell division is often regulated by extracellular signals. In budding yeast, signaling from mating pheromones arrests the cell cycle in G1 phase [1]. This arrest requires the protein Far1 [2], which is thought to antagonize the G1/S transition by acting as a Cdk inhibitor (CKI) [3, 4], al...

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Detalhes bibliográficos
Main Authors: Pope, Patricia A., Bhaduri, Samyabrata, Pryciak, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086830/
https://ncbi.nlm.nih.gov/pubmed/24909323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.05.002
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